shingles vaccine ingredients cdc

The CDC found that Shingrix. People with weakened immune systems also have a higher risk of getting shingles and complications from the disease. DTap-HepB-IPV (diphtheria, tetanus, pertussis, hepatitis B, & polio), 10. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. AS01B is made of up MPL, a purified fat-like substance, and QS-21 which is purified from. More information about contraindications and precautions. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. So its very important that you get this vaccine. 2012 Oct 19;30(47):6636-41. Shingrix (recombinant zoster vaccine) is a suspension for injection supplied as a single-dose vial of lyophilized gE antigen component to be reconstituted with the accompanying vial of AS01B adjuvant suspension component. MMWR. 2017 Dec 19:35(52):7231-7239. Harpaz R, Ortega-Sanchez IR, Seward JF. VAERS is only for reporting reactions, and VAERS staff members do not give medical advice. DTaP-IPV-Hib-HepB Vaccine(diphtheria, tetanus, pertussis, polio, haemophilus influenzae type B, & hepatitis B), Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus, Haemophilus b Conjugate [Meningococcal Protein Conjugate] and Hepatitis B [Recombinant] Vaccine, Muellers growth medium, ammonium sulfate, formaldehyde, Mueller-Miller casamino acid medium without beef heart infusion, aluminum phosphate, Stainer-Scholte medium, casamino acids, dimethyl-betacyclodextrin, glutaraldehyde, Vero cells, yeast Saccharomyces cerevisiae, yeast, soy peptone, dextrose, amino acids, mineral salts, phosphate buffer, alum (potassium aluminum sulfate), amorphous aluminum hydroxyphosphate sulfate, nicotinamide adenine dinucleotide, hemin chloride, soy peptone, dextrose, mineral salts, N. meningitidis serogroup B, filamentous hemagglutinin (FHA), pertactin (PRN), fimbriae types 2 and 3 (FIM), aluminum, polysorbate 80, formaldehyde, glutaraldehyde, bovine serum albumin, neomycin, streptomycin sulfate, polymyxin B sulfate, ammonium thiocyanate, yeast protein, 12. Tdap Vaccine(tetanus, diphtheria, & pertussis), Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed, Stainer-Scholte medium, casamino acids, dimethylbeta-cyclodextrin, glutaraldehyde, formaldehyde, aluminum phosphate, Mueller-Miller casamino acid medium without beef heart infusion, ammonium sulfate, modified Muellers growth medium, aluminum phosphate, formaldehyde, glutaraldehyde, 2-phenoxyethanol, water, modified Latham medium derived from bovine casein, Fenton medium containing a bovine extract, formaldehyde, modified Stainer-Scholte liquid medium, glutaraldehyde, aluminum hydroxide, aluminum hydroxide, sodium chloride, formaldehyde, polysorbate 80 (Tween 80), Manufacturer: Pfizer Ireland Pharmaceuticals, chick embryo fibroblast (CEF) cells, formaldehyde, sucrose gradient, aluminum hydroxide, human serum albumin, aluminum hydroxide, sodium chloride, dibasic sodium phosphate, monobasic potassium phosphate, formaldehyde, sucrose, protamine sulfate, chick protein, DNA from CEF cells, neomycin, gentamicin, gelatin capsules, sucrose, ascorbic acid, amino acid mixture, lactose, magnesium stearate, Typhoid Vaccine Live Oral TTyphoid Vi Polysaccharide Vacciney21a, semisynthetic medium, casein derived raw materials, hexadecyltrimethylammonium bromide, formaldehyde, formaldehyde, phenol, polydimethylsiloxane, fatty-acid ester-based antifoam, isotonic phosphate buffered saline, sodium chloride, disodium phosphate, monosodium phosphate, water, Varivax Refrigerator Package Insert (undated), Frozen: human embryonic lung cell cultures, embryonic guinea pig cell cultures, human diploid cell cultures (WI-38), Refrigerator: human embryonic lung cell cultures, embryonic guinea pig cell cultures, human diploid cell cultures (WI-38), Frozen: sucrose, phosphate, glutamate, processed gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride. Most side effects are mild to moderate lasting 2-3 daysand could affect normal daily activities. Viruses can be grown in chicken eggs before being used in vaccinations. You will be subject to the destination website's privacy policy when you follow the link. MMR & Varicella (measles, mumps, rubella, & chickenpox), 33. Two doses of Shingrix are more than 90% effective at preventing shingles. Live mice brains are inoculated with the Japanese encephalitis virus to grow the virus used in the vaccine. Note: Zoster vaccine live (Zostavax) is no longer available for use in the United States, as of November 18, 2020. 8. Saving Lives, Protecting People, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. A single dose after reconstitution is 0.5 mL. Vaccines for preventing herpes zoster in older adults. You will be subject to the destination website's privacy policy when you follow the link. Shingrix is now covered by most health insurance plans. You should tell patients to expect such reactions as pain, swelling, and redness . These side effects may temporarily prevent a vaccinated person from doing regular activities. Hib Vaccine(haemophilus influenzae type B), Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate), amorphous aluminum hydroxyphosphate sulfate (previously referred to as aluminum hydroxide), sodium chloride, Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate), semi-synthetic medium, ammonium sulfate, Mueller and Miller medium, milk-derived raw materials (casein derivatives), saline diluent, purified capsular polysaccharide, synthetic medium, semi-synthetic medium, formaldehyde, lactose, sterile saline solution, purified capsular polysaccharide, lactose, formaldehyde, aluminum hydroxide, amino acid supplement, phosphate-buffered saline solution, polysorbate 20, MRC-5 cellular proteins, formalin, neomycin sulfate, MRC-5 diploid fibroblasts, amorphous aluminum hydroxyphosphate sulfate, nonviral protein, DNA, bovine albumin, formaldehyde, neomycin, amorphous aluminum hydroxyphosphate sulfate, sodium borate, sodium chloride, 16. Below are the proper citations for this page according to four style manuals (in alphabetical order): the Modern Language Association Style Manual (MLA), the Chicago Manual of Style (Chicago), the Publication Manual of the American Psychological Association (APA), and Kate Turabian's A Manual for Writers of Term Papers, Theses, and Dissertations (Turabian). Vaccine. There are currently two shingles vaccines licensed and available for use in the United States: Shingrix (recombinant zoster vaccine) and Zostavax (zoster vaccine live). About 1 out of 6 people had symptoms severe enough to prevent them from doing regular activities. All information these cookies collect is aggregated and therefore anonymous. Baxter R, Tran TN, Hansen J, Emery M, Fireman B, et al. The efficacy of two doses of Shingrix for the prevention of postherpetic neuralgia (PHN) was high: 91.2% in adults aged 50 years and older, and 88.8% in adults aged 70 years and older. Vaccine. Cookies used to make website functionality more relevant to you. Redness and swelling can also happen at the site of the injection. PHN occurs in the areas where the shingles rash was and can last for months or years after the rash goes away. Managing Editor Common Ingredients: L-alanine, L-arginine (free base), Common Ingredients: glucose, sodium bicarbonate, L-glutamine, pyridoxine HCl, pyridocal HCl, folic acid, phenol red, HEPES (2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid), L-methionine, L-cystine, sodium phosphate mono-basic, sodium pyruvate, vitamins, Common Ingredients: inorganic salts, D-glucose, phenol red, calcium, magnesium salts. You can review and change the way we collect information below. Most people (78%) who got Shingrix reported at least some pain at the injection site. The FDA adds that individuals older than 18 at a higher risk of shingles are also eligible for the vaccine. They help us to know which pages are the most and least popular and see how visitors move around the site. yeast protein, amorphous aluminum hydroxyphosphate sulfate, formaldehyde. Consider delaying vaccination if your patient is pregnant, lactating, or experiencing an acute episode of shingles. Contact the Centers for Disease Control and Prevention (CDC): The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Chicago, Illinois 60654 USA, Natalie Leppard Shingrix provides stronger protection against shingles compared to Zostavax. This long-lasting pain is called postherpetic neuralgia (PHN), and it is the most common complication of shingles. ACIP will review evidence for Shingrix in immunocompromised people as it becomes available. Shingles is a painful rash that usually develops on one side of the body, often the face or torso. Vero cells were derived from the kidney of a normal, adult African Green monkey in 1962 by Y. Yasumura and Y. Kawakita. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. The two doses should be separated by two to six months. Accessed February 21, 2023. https://vaccines.procon.org/vaccine-ingredients-and-manufacturer-information/, Born Gay? After you have chickenpox, the virus stays in your body and can cause shingles later in life. aluminum hydroxide, sodium chloride, phosphate buffers [disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate], Hepatitis B Vaccine (Recombinant), Adjuvanted, Manufacturer: Dynavax Technologies Corporation, Hansenula polymorpha yeast, fermentation media [vitamins, mineral salts], CpG 1018 adjuvant [22-mer phosphorothioate linked oligodeoxynucleotide, phosphate buffered saline (sodium chloride, sodium phosphate, dibasic dodecahydrate, monobasic dihydrate, polysorbate 80)], yeast protein, yeast DNA, deoxycholate, CpG 1018, Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine, Recombinant, Saccharomyces cerevisiae, fermentation media [vitamins, amino acids, mineral salts, carbohydrates], amorphous aluminum hydroxyphosphate sulfate, amorphous aluminum hydroxyphosphate sulfate adjuvant, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus 9-valent Vaccine, Recombinant, amorphous aluminum hydroxyphosphate sulfate, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus Bivalent (Types 16, 18) Vaccine, Recombinant, serum-free culture media [lipids, vitamins, amino acids, mineral salts], hydroxide salt, AS04 [3-O-desacyl-4-monophosphoryl lipid A (MPL), hydroxide salt, sodium chloride, sodium dihydrogen phosphate dihydrate, water, 3-O-desacyl-4-monophosphoryl lipid A (MPL), aluminum hydroxide, sodium chloride, sodium dihydrogen phosphate dihydrate, insect cell and viral protein, bacterial cell protein, 19. Aluminum is used in vaccines as an adjuvant, which helps the vaccine work more quickly and more powerfully. According to the CDC, the risk of shingles is approximately 2 to 4 times higher among people with autoimmune disorders. in adults aged 18 years and older who are or will be at increased risk of HZ due to immunodeficiency or immunosuppression caused by known disease or therapy. Cochrane Database Syst Rev. Call your doctor at once if you have a high fever. Common side effects, such as soreness and redness at the injection site, are usually mild to moderate in intensity and resolve quickly on their own. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Tell your provider if you feel dizzy or have vision changes or ringing in the ears. Many people also feel tired or have muscle pain, a headache, shivering, fever, stomach pain, or nausea. If a problem is found with a vaccine, CDC and FDA will inform health officials, health care providers, and the public. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. problems with balance or eye movement; or. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. in adults aged 18 years and older who are or will be at increased risk of. 2021), sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, and polysorbate 20 (Tween20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100, Influenza Vaccine,Live, Intranasal (Quadrivalent, Types A and Types B), FluMist Quadrivalent Package Insert (Aug. 2021), specific pathogen-free (SPF) eggs, stabilizing buffer, monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin sulfate, ethylenediaminetetraacetic acid (EDTA), Influenza Virus Vaccine (Quadrivalent, Types A and Types B), Manufacturer: Glaxosmithkline Biologicals, Fluarix Quadrivalent Package Insert (2021), octoxynol-10 (TRITON X-100), tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, Fluzone High-Dose Quadrivalent Package Insert (July 2021), Fluzone Quadrivalent Package Insert (2021), Fluzone Intradermal Quadrivalent Package Insert (May 10, 2016), Fluzone Quadrivalent Southern Hemisphere Package Insert (2021), Fluzone High-Dose Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution , octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Intradermal Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 17 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent Southern Hemisphere: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone High-Dose Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone Quadrivalent: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Intradermal Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Quadrivalent Southern Hemisphere: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Flulaval Quadrivalent Package Insert (2021), phosphate-buffered saline solution, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Japanese Encephalitis Virus Vaccine, Inactivated, Adsorbed, Vero cells, protamine sulfate, sucrose density gradient, formaldehyde, aluminum hydroxide, formaldehyde, bovine serum albumin, host cell DNA, sodium metabisulphite, host cell protein, protamine sulfate, 23. 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